摘要
目的 分析腔镜超声引导下微波消融(MWA)治疗肝癌的预后影响因素.方法 回顾性分析行腔镜超声引导下MWA治疗的105例肝癌患者的临床相关资料.所有患者治疗后均随访3年,按其预后分为生存组(n=65)与死亡组(n=40),应用多因素Logistic回归模型分析影响腔镜超声引导下MWA治疗肝癌预后的相关因素.结果 单因素分析显示:性别、年龄、体重指数(BMI)与腔镜超声引导下MWA治疗肝癌的预后无关(P＞0.05);基础疾病、肿瘤数量、肿瘤直径、分化程度、Child-Pugh分级、肝炎病史、肿瘤进展与腔镜超声引导下MWA治疗肝癌的预后有关(P＜0.05);多因素Logistic回归分析显示:有基础疾病、肿瘤多发、肿瘤直径＞5 cm、低分化、Child-PughB级、有肝炎病史、肿瘤发生进展是影响腔镜超声引导下MWA治疗肝癌预后的高危因素(P＜0.05).结论 腔镜超声引导下MWA治疗肝癌的预后与基础疾病、肿瘤多发、肿瘤直径＞5 cm、低分化等有关,临床需予以高度重视.
Abstract
Objective To analyze the prognostic factors of laparoscopic ultrasound-guided microwave ablation(MWA)in the treatment of liver cancer.Methods A retrospective analysis was conducted on the clinical data of 105 liver cancer patients who underwent endoscopic ultrasound guided MWA treatment.All patients were followed up for 3 years after treatment and divided into survival group(n=65)and death group(n=40)based on their prognosis.A multivariate logistic regression analysis model was used to analyze the relevant factors affecting the prognosis of liver cancer treated with MWA guided by endoscopic ultrasound.Results Univariate analysis showed that gender,age,body mass index(BMI)were not associated with the prognosis of liver cancer treated with MWA guided by endoscopic ultrasound(P＞0.05);The prognosis of liver cancer treated with MWA guided by endoscopic ultrasound is related to basic disease,tumor quantity,tumor diameter,differentiation degree,Child Pugh grading,histo-ry of hepatitis,tumor progression(P＜0.05);Multivariate logistic regression analysis showed that having underlying diseases,mul-tiple tumors,tumor diameter＞5 cm,low differentiation,Child Pugh B grade,history of hepatitis,and tumor progression were high-risk factors affecting the prognosis of laparoscopic ultrasound-guided MWA treatment for liver cancer(P＜0.05).Conclusion The prognosis of laparoscopic ultrasound-guided MWA treatment for liver cancer is related to underlying diseases,multiple tumors,tumor diameter＞5cm,and low differentiation,which should be highly valued in clinical practice.
维普
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