High Risk Factors of Acute Renal Injury in Patients with Primary Liver Cancer After Laparoscopic Radical Surgery
Objective To explore the influencing factors of acute renal injury(AKI)in patients with primary liver canc-er(PLC)after laparoscopic radical surgery,and to provide reference for clinical prevention and treatment of AKI.Methods A total of 100 PLC patients were selected as the study subjects.According to whether AKI occurred after laparoscopic radical surger-y,they were divided into the occurrence group and the non-occurrence group.The basic data of the 2 groups were collected,and the single factor analysis was performed first.After the different items were obtained,the logistic regression analysis was performed to obtain the independent risk factors affecting the occurrence of AKI in PLC patients after laparoscopic radical surgery.Results 14 cases of AKI occurred in 100 patients with PLC after laparoscopic radical surgery,the incidence was 14.00％(14/100);The operation time,intraoperative blood loss,diabetes,serum albumin level,creatinine level,uric acid level and hemoglobin were sig-nificantly different between the 2 groups(P＜0.05);Multiple factors showed that the operation time ≥2 h,intraoperative bleeding≥500 ml,diabetes,serum albumin level＜35 g/L,creatinine level ≥70 μmol/L,uric acid level ≥360 µmol/L and hemoglobin＜100 g/L were high risk factors of AKI in PLC patients after laparoscopic radical surgery(P＜0.05 and OR＞1).Conclusion Operation time ≥2 h,intraoperative blood loss ≥500 ml,diabetes,serum albumin level＜35 g/L,creatinine level ≥70 μmol/L,uric acid level ≥360 µmol/L and hemoglobin＜100 g/L are the high risk factors that affect the occurrence of AKI in PLC pa-tients after laparoscopic radical surgery.It is also necessary to identify the above factors as early as possible and carry out targeted intervention to reduce the risk of AKI and improve the prognosis of patients.
万方数据
维普
