Effects of Serum CA125,D-D Levels and Residual Lesion Size on Tumor-free Survival in Patients with Recurrent Ovarian Cancer After Surgery
Objective To explore the effects of serum carbohydrate antigen 125(CA125),D-Dimer(D-D)levels and re-sidual lesion size on tumor-free survival in patients with recurrent ovarian cancer after surgery.Methods The clinical data of 50 patients with recurrent ovarian cancer were retrospectively analyzed,and the disease-free survival time was followed up and recor-ded.General data and postoperative serum CA125 and D-D levels of patients were analyzed,factors influencing disease-free sur-vival were analyzed.Pearson correlation coefficient was used to analyze the correlation between postoperative CA125,D-D levels,residual lesion size and tumor-free survival.Results Tumor free survival of patients with different clinical stage,differentiation degree,chemotherapy course,CA125,D-D level and residual lesion size were statistically significant(P＜0.05).COX regression analysis showed that preoperative clinical stage,postoperative CA125 level,postoperative D-D level and postoperative residual le-sion size were independent influencing factors for tumor free survival of patients with recurrent ovarian cancer(P＜0.05).Pearson correlation analysis showed that postoperative CA125,D-D levels and residual lesion size were negatively correlated with tumor-free survival(P＜0.05).Conclusion Postoperative CA125 and D-D levels and residual lesion size are important factors affect-ing tumor free survival in patients with recurrent ovarian cancer.
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