The Effect of Thoracoscopic Minimally Invasive Surgery on Serum Tumor Markers and T Lymphocyte Subsets in Lung Cancer Patients
Objective To investigate the effects of thoracoscopic minimally invasive surgery on serum tumor markers and T lymphocyte subsets in lung cancer patients.Methods 104 lung cancer patients were divided into 2 groups according to differ-ent surgical treatment plans,with 52 cases in each group.The control group received traditional open chest surgery treatment,while the study group received thoracoscopic minimally invasive surgery treatment.Compare the levels of surgical related indica-tors,serum tumor markers,and T lymphocyte subsets between the 2 groups,and conduct safety assessments.Results The surgical time,intraoperative blood loss,and postoperative recovery time of the study group were lower than those of the control group,and the differences were statistically significant(P＜0.05);There was no statistically significant difference in lymph node dissection between the 2 groups(P＞0.05).24 hours after surgery,the serum levels of carcinoembryonic antigen(CEA)and carbohydrate antigen 125(CA125)in both groups were lower than before surgery(P＜0.05),but there was no statistically significant differ-ence in serum CEA and CA125 levels between the 2 groups(P＞0.05).7 days after surgery,the levels of CD3+,CD4+,CD8+,and CD4+/CD8+in both groups were lower than before surgery,but the study group was higher than the control group,with statis-tical significance(P＜0.05).The treatment safety of the research group was better than that of the control group,and the differ-ence was statistically significant(P＜0.05).Conclusion Thoracoscopic minimally invasive surgery has significant advantages in treating lung cancer,reducing serum tumor marker levels and alleviating the impact of surgical treatment on T lymphocyte subsets with fewer complications,higher safety,and is easily accepted by patients.
NETL
NSTL
万方数据
