Objective To analyze the prognostic factors related to early non Hodgkin's lymphoma(NHL)patients in the primary nasal cavity.Methods 105 patients with early primary nasal NHL were selected and followed up for 2 years.The pa-tients were divided into the poor prognosis group(mortality)and the good prognosis group(survival)based on their survival sta-tus.The data of the 2 groups were compared and Cox regression analysis was used to analyze the relevant factors affecting the prognosis of early primary nasal NHL patients.Results After a 2-year follow-up,the prognosis was statistically analyzed.Among 105 patients with early primary nasal NHL,22 died with a mortality rate of 20.95%(22/105),and 83 survived with a survival rate of 79.05%(83/105).The survival curve drawn by KM method showed that the average survival time of 22 patients who died was(12.32±4.48)months;The clinical stage,serum neutrophil to lymphocyte ratio(NLR),interleukin-6(IL-6),and C-reactive protein(CRP)levels in patients with poor prognosis were higher than those in patients with good prognosis,with statistically sig-nificant differences(P<0.05);The results of Cox regression analysis showed that clinical stage Ⅱ,high NLR levels,IL-6 levels,and CRP levels were all associated with poor prognosis in patients with early primary nasal NHL(P<0.05).Conclusion The prognosis of early primary nasal NHL patients is not ideal,which is related to clinical staging and high levels of serum NLR,IL-6,and CRP.
Non Hodgkin's lymphomaCavidade nasal PrognosisInfluence factor