Effect of Radiotherapy Using Three-Dimensional vs Two-Dimensional Afterloading Tech-nique on Radiation Dose to Bladder,Sigmoid Colon and Rectum in Patients with Cervical Cancer
Objective To discuss the effect of radiotherapy using three-dimensional vs two-dimensional afterloading technique on radiation dose to bladder,sigmoid colon and rectum in patients with cervical cancer.Methods 55 patients with cer-vical cancer were divided into 2 groups according to post-loading treatment techniques:2D group(25 cases)and 3D group(30 ca-ses).All patients received intensity-modulated external radiotherapy and cisplatin synchronous chemotherapy,2D group received 2D post-loading radiotherapy,and 3D group received 3D post-loading radiotherapy.Clinical efficacy of the 2 groups was observed and compared.Rectal and bladder irradiation doses,acute adverse reactions to radiotherapy.Results The clinical efficacy rate of 3D group(96.67％)was higher than that of 2D group(80.00％)(P＜0.05).The doses received to bladder and rectum after treatment in 3D group were lower than those in 2D group(P＜0.05).The incidence rates of acute proctitis,cystitis and sigmoid-itis in the three-dimensional group were 76.67％,10.00％and 3.33％,respectively,lower than those in the two-dimensional group(96.00％,32.00％and 20.00％),P＜0.05.Conclusion Compared with 2D posterior radiotherapy,3D posterior radio-therapy has better clinical therapeutic effect and lower dose to the dangerous organs of rectum and bladder,so as to reduce the a-cute adverse reactions after radiotherapy.
万方数据
维普
