首页|胸腔镜下两种不同术式对早期NSCLC患者的疗效及对其肺功能和预后等的影响

胸腔镜下两种不同术式对早期NSCLC患者的疗效及对其肺功能和预后等的影响

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目的 探讨胸腔镜下两种不同术式对早期NSCLC患者的疗效及对其肺功能和预后等的影响.方法 选取88例早期NSCLC患者(均为Ⅰ A1期),根据术式差异分为2组.研究组40例,采用胸腔镜下肺楔形切除术治疗,而对照组48例则采用胸腔镜下解剖性肺段切除术治疗,比较2组的临床疗效等差异.结果 研究组的手术时间、术中出血量及术后并发症发生率及术后住院时间均优于对照组(P<0.05).术后2组的肺功能指标均较术前降低,且对照组下降更甚(P<0.05);术后2组的炎性指标均较术前升高,且对照组升高更甚(P<0.05).术后1年,2组的总生存率及复发率比较,无统计学差异(P>0.05).结论 胸腔镜下肺楔形切除术对早期NSCLC患者的疗效更佳,不仅可缩短手术时间,加快患者术后恢复,同时对肺功能的影响较小,且可降低患者术后的炎性反应程度,最终不影响患者的预后,值得临床推广应用.
Evaluation of the Efficacy of Two Different Thoracoscopic Procedures in Patients with Early-stage NSCLC and the Impact on Their Lung Function and Prognosis
Objective To investigate the efficacy of 2 different thoracoscopic procedures in patients with early-stage NSCLC and the impact on their lung function and prognosis.Methods 88 patients with early-stage NSCLC(all stage Ⅰ A1)were selected and divided into 2 groups according to the differences in the surgical procedures.Among them,40 patients in the study group were treated by thoracoscopic pulmonary wedge resection,while 48 patients in the control group were treated by thoracoscop-ic anatomical segmental lung resection,comparing the clinical efficacy and other differences between the 2 groups.Results The operating time,intraoperative bleeding,postoperative complication rate and postoperative hospital stay were all better in the study group than in the control group(P<0.05);The postoperative pulmonary function indexes in both groups were lower than before surgery,and more so in the control group(P<0.05);The inflammatory indexes were higher in both groups after surgery,and more so in the control group(P<0.05);One year after surgery,there was no difference in the overall survival rate and recurrence rate between the 2 groups(P>0.05).Conclusion Thoracoscopic pulmonary wedge resection has better efficacy for patients with ear-ly stage NSCLC,which not only shortens the operation time and accelerates the postoperative recovery of patients,but also has less impact on lung function and reduces the degree of inflammatory response of patients after surgery,which ultimately does not affect the prognosis of patients and is worthy of clinical promotion and application.

Non-small cell lung cancerThoracoscopic pulmonary wedge resectionAnatomic segmental lung resectionEfficacyLung functionPrognosis

孙继红、朱正帅、刘丽

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473000 河南省南阳市中心医院

非小细胞肺癌 胸腔镜下肺楔形切除术 解剖性肺段切除术 疗效 肺功能 预后

2024

实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
年,卷(期):2024.39(9)
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