Predictive Value of Preoperative PLT,White Blood Cell Count,NLR and PLR Levels for Prognosis of Patients with Esophageal Cancer
Objective To investigate the value of preoperative platelet(PLT),white blood cell count,neutrophil-lympho-cyte ratio(NLR)and peripheral blood cell to lymphocyte ratio(PLR)in predicting the prognosis of esophageal cancer.Methods A total of 100 patients with esophageal cancer were selected to detect PLT,white blood cell count,NLR and PLR levels were de-tected before radical resection of esophageal cancer.The patients were followed up for 2 years,and were divided into recurrence group(36 cases)and non-recurrence group(64 cases)according to their prognosis.The levels of the above indexes were com-pared in patients with different prognosis.The factors affecting the prognosis of esophageal cancer were analyzed by multivariate COX regression.The ROC curve was drawn to evaluate the predictive value of PLT,white blood cell count,NLR and PLR on the prognosis of esophageal cancer patients.Results The level of PLT in recurrent group was significantly lower than that in non-re-current group(P＜0.05),and the number of white blood cells,PLR and NLR were significantly higher than those in non-recurrent group(P＜0.05).Multivariate COX analysis showed that NLR,PLT,PLR and white blood cell count were the prognostic factors of esophageal cancer(P＜0.05).The ROC curve was drawn to evaluate the prognostic value of PLT,white blood cell count,PLR and NLR in patients with esophageal cancer.The results showed that the sensitivity and specificity of NLR and PLT are the high-est when detected separately,and the sensitivity and specificity are the highest when detected jointly.Conclusion The preopera-tive white blood cell count,PLR,NLR,and PLT levels are related to the prognosis of esophageal cancer patients,the combined de-tection of the four is more valuable in predicting the prognosis of esophageal cancer.
Esophageal cancerWhite blood cellsPlateletNeutrophil-to-lymphocyte ratioPeripheral blood cell to lym-phocyte ratioPeripheral blood cell to lymphocyte ratioPrognosis
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