The Effect of Endoscopic Minimally Invasive Surgery on Postoperative Immune Function and Recurrence Rate of Early Esophageal Cancer
Objective To investigate the effects of endoscopic minimally invasive surgery on immune function and recur-rence rate of early esophageal cancer.Methods 112 patients with early esophageal cancer were randomly divided into the control group and the observation group,56 cases in each group.The control group underwent endoscopic mucosal resection(EMR),and the observation group underwent endoscopic submucosal dissection(ESD).The operation-related indexes,immune function(CD3+,CD4+,CD8+),complications and recurrence rate of the 2 groups were observed.Results Compared with the control group,the operation time in the observation group was significantly shorter and the amount of blood loss was significantly less(P＜0.05).The levels of CD3+and CD4+in the observation group were higher than those in the control group,and CD8+were lower than those in the control group(P＜0.05).The incidence of complications in the observation group(5.36％)was significantly lower than that in the control group(19.64％)(P＜0.05).The recurrence rate in the observation group(5.36％)was signifi-cantly lower than that in the control group(17.86％)(P＜0.05).Conclusion ESD therapy for early esophageal cancer patients has less blood loss,shorter operation time,not only can reduce the incidence of postoperative complications and recurrence risk,but also reduce the impact on the immune function of patients.
Early esophageal cancerEndoscopic minimally invasive surgeryImmune functionRecurrence rate
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