Analysis of Risk Factors for Postoperative PE in Patients with Gastrointestinal Cancer Underwent Laparoscopic Surgery
Objective To explore the risk factors of pulmonary embolism(PE)after laparoscopic surgery in patients with gastrointestinal cancer.Methods 852 patients with gastrointestinal cancer who underwent laparoscopy were collected as the study subjects.According to whether PE occurred after surgery,they were grouped into PE group and non PE group.Clinical data were collected from all patients,and Logistic regression analysis models were applied to analyze the risk factors for postoperative PE in patients with gastrointestinal cancer underwent laparoscopic surgery.Results A total of 68 out of 852 patients with gastrointesti-nal cancer developed PE,with a PE incidence rate of 7.98％(68/852).The proportions of patients with age ≥60 years,intraop-erative pneumoperitoneum pressure＞15 mmHg,postoperative bed rest time≥ 3 days,history of cerebral infarction,combined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis were higher than that in the non PE group,and the operation time in PE group were longer than those in non PE group,the differences are statistically signifi-cant(P＜0.05).Multivariate Logistic regression analysis showed that age ≥60 years,long operation time,intraoperative pneumo-peritoneum pressure＞15mmHg,postoperative bed rest time ≥3 days,history of cerebral infarction,combined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis were all independent risk factors for PE af-ter laparoscopic surgery in patients with gastrointestinal cancer(P＜0.05).Conclusion Age ≥60 years,long operation time,in-traoperative pneumoperitoneum pressure＞15 mmHg,postoperative bed rest time≥3 days,history of cerebral infarction,com-bined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis are all risk factors for PE after laparoscopic surgery in patients with gastrointestinal cancer.In clinical practice,attention should be paid to patients with gastrointestinal cancer who possess the above characteristics,and early intervention and treatment should be done to prevent or re-duce the occurrence of PE and improve prognosis of patients.
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