Analysis of Influencing Factors of Anastomotic Stenosis in Patients with Low Colorectal Cancer After Intersphincteric Resection
Objective To investigate the factors affecting anastomotic stenosis after intersphincteric resection(ISR)in patients with low colorectal cancer.Methods A total of 80 patients with low colorectal cancer treated by ISR were selected and divided into a narrow group(n=15)and a non-narrow group(n=65)according to whether anastomotic stenosis occurred after surgery,and the risk factors for the occurrence of anastomotic stenosis were investigated.Results Univariate analysis showed sig-nificant differences between the 2 groups in terms of gender,distance from lower tumor margin to anal margin,preoperative neoad-juvant radiotherapy,inflammatory bowel disease,diabetes mellitus,and postoperative anastomotic fistulae(P＜0.05).There were no significant differences in terms of age,body mass index,hypertension,preoperative hemoglobin,albumin,total protein,TNM stage,maximum tumor diameter,tumor differentiation degree,ISR procedure,operation time,intraoperative blood loss,submesen-teric artery dissection level,and anastomotic height between the 2 groups(P＞0.05).Multifactorial analysis suggested that male,preoperative neoadjuvant radiotherapy,inflammatory bowel disease,diabetes and postoperative anastomotic fistula were independ-ent risk factors for anastomotic stenosis(P＜0.05).Conclusion Male,preoperative neoadjuvant radiotherapy,inflammatory bow-el disease,diabetes,postoperative anastomotic fistula may induce anastomotic stenosis in patients with low colorectal cancer after ISR,and corresponding intervention measures should be taken to reduce the incidence of anastomotic stenosis.
万方数据
维普
