实用癌症杂志2024,Vol.39Issue(10) :1718-1720.DOI:10.3969/j.issn.1001-5930.2024.10.038

扶正固本汤与神阙灸联合化疗治疗晚期大肠癌的临床观察

Clinical Observation on the Combination of Fuzheng Guben Tang and Shenque Moxibustion with Chemotherapy in the Treatment of Advanced Colorectal Cancer

张新颖 王红梅 王丽丽
实用癌症杂志2024,Vol.39Issue(10) :1718-1720.DOI:10.3969/j.issn.1001-5930.2024.10.038

扶正固本汤与神阙灸联合化疗治疗晚期大肠癌的临床观察

Clinical Observation on the Combination of Fuzheng Guben Tang and Shenque Moxibustion with Chemotherapy in the Treatment of Advanced Colorectal Cancer

张新颖 1王红梅 1王丽丽1
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作者信息

  • 1. 453003 新乡医学院第三附属医院
  • 折叠

摘要

目的 分析扶正固本汤与神阙灸联合化疗治疗晚期大肠癌患者的效果.方法 选取85例晚期大肠癌患者,根据随机数字表法分为对照组(42例)与研究组(43例).对照组行常规化疗,研究组则加以扶正固本汤与神阙灸治疗,21 d为1个治疗周期,持续治疗2个周期.统计比较2组免疫功能、癌因性疲乏、不良反应.结果 治疗前,2组CD3+、CD4+、CD8+与癌症疲乏量表(CFS)各维度评分相比,差异无统计学意义(P>0.05);治疗后,研究组CD3+、CD4+高于对照组、CFS各维度评分低于对照组,差异有统计学意义(P<0.05);2组不良反应比较,差异无统计学意义(P>0.05).结论 扶正固本汤与神阙灸联合化疗治疗晚期大肠癌效果显著,可减少化疗对机体免疫系统的损伤,减轻癌因性疲乏,且无严重不良反应,具有一定的应用价值.

Abstract

Objective To analyze the effect of Fuzheng Guben Tang and Shenque Moxibustion combined with chemo-therapy in the treatment of advanced colorectal cancer patients.Methods 85 patients with advanced colorectal cancer were se-lected and randomly divided into the control group(42 cases)and the study group(43 cases)using a random number table meth-od.The control group received routine chemotherapy,while the study group received treatment with Fuzheng Guben Tang and Shenque Moxibustion.The treatment period was 21 days,with a duration of 2 cycles.Compared the immune function,cancer-relat-ed fatigue,and adverse reactions between the 2 groups.Results Before treatment,there was no statistically significant difference(P>0.05)in the scores of CD3+,CD4+,CD8+and various dimensions of the Cancer Fatigue Scale(CFS)between the two groups;After treatment,the CD3+and CD4+levels in the study group were higher than those in the control group,and the CFS scores in all dimensions were lower than those in the control group,with statistically significant differences(P<0.05);There was no statistically significant difference in adverse reactions between the 2 groups(P>0.05).Conclusion The combination of Fuzheng Guben Tang and Shenque Moxibustion with chemotherapy has a significant effect on the treatment of advanced colorectal cancer.It can reduce the damage of chemotherapy to the body's immune system,alleviate cancer-related fatigue,and have no seri-ous adverse reactions.It has certain application value.

关键词

晚期大肠癌/化疗/扶正固本汤/神阙灸/免疫功能/不良反应

Key words

Advanced stage colorectal cancer/Chemotherapy/Fu Zheng Gu Ben Tang/Shenque Moxibustion/Immune function/Adverse reactions

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出版年

2024
实用癌症杂志
江西省肿瘤医院 江西省肿瘤研究所

实用癌症杂志

影响因子:1.241
ISSN:1001-5930
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