Comparison of Efficacy and Complications of Endoscopic Mucosal Dissection in Patients with Early Esophageal Cancer with Different Lesion Lengths
Objective To explore and compare the efficacy and complications of endoscopic mucosal dissection in pa-tients with early esophageal cancer with different lesion lengths.Methods 65 patients with early esophageal cancer with lesion length＜3 cm who underwent endoscopic mucosal dissection were collected as the control group,and 85 patients with early esoph-ageal cancer with lesion length＞3 cm were included in the test group.The lesion resection effect,perioperative condition,serum tumor markers before treatment and at 3 months after treatment and incidence rates of complications were compared between the 2 groups.Results There were no differences in the en bloc resection rate and total resection rate between groups(P＞0.05).The surgical time and postoperative fasting time in test group were longer than those in the control group(P＜0.05),but there were no differences in antibiotic use time and hospital stay(P＞0.05).After 3 months of treatment,the levels of CEA,SCC-Ag and CA19-9 in both groups were reduced compared with those before treatment(P＜0.05),but there were no differences in the levels of CEA,SCC-Ag and CA19-9 between both groups(P＞0.05).The incidence rates of complications were higher in test group than those in the control group(P＜0.05).Conclusion Endoscopic mucosal dissection has similar resection effect,tumor markers levels after 3 months,anti biotic use time and hospital stay in patients with early esophageal cancer with different lesion lengths.The surgical time,postoperative feeding time and incidence rates of complications of patients with longer length of lesion are slightly longer or higher than those of patients with shorter length of lesion,which has clinical significance.
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