高场磁共振多b值弥散加权成像对肝细胞癌与肝血管瘤的鉴别诊断价值分析
Analysis of the Differential Diagnostic Value of High-field Magnetic Resonance Multi b-value Diffusion-weighted Imaging for Hepatocellular Carcinoma and Hepatic Hemangioma
郭凯 1孙勇 1杨明 1丁会1
作者信息
摘要
目的 分析高场磁共振(MRI)多b值弥散加权成像(DWI)对肝细胞癌与肝血管瘤中的鉴别诊断价值.方法 选取行高场MRI-DWI检查的109 例患者,所有患者病情经病理检查明晰,43 例肝细胞癌患者划入观察组,66 例肝血管瘤患者划入对照组,对比两组不同b值下的表观弥散系数(ADC)值;另绘制受试者工作曲线(ROC),分析不同b值下ADC值鉴别诊断肝细胞癌与肝血管瘤的效能.结果 b值为50 s/mm2、400 s/mm2、1000 s/mm2 时,观察组的ADC值分别为(2.09±0.42)×10-3/mm2/s、(1.72±0.36)×10-3/mm2/s、(1.39±0.28)×10-3/mm2/s,均低于对照组的(2.45±0.57)×10-3/mm2/s、(2.16±0.45)×10-3/mm2/s、(1.88±0.47)×10-3/mm2/s,有统计学差异(P＜0.05);ROC结果显示:当b值在1000 s/mm2 时,ADC值鉴别诊断肝细胞癌与肝血管瘤的曲线下面积(AUC)、敏感度、特异度最高,分别为0.816、90.70%、72.70%.结论 高场MRI-DWI能够有效鉴别诊断出肝细胞癌与肝血管瘤,且b值越大,诊断效果越强,具有一定的应用价值.
Abstract
Objective To analyze the differential diagnostic value of high field magnetic resonance imaging(MRI)multi b-value diffusion-weighted imaging(DWI)in hepatocellular carcinoma and hepatic hemangioma.Methods A total of 109 patients who underwent high-field MRI-DWI examination were selected,and their conditions were clarified through pathological examina-tion.43 patients with hepatocellular carcinoma were assigned to the observation group,and 66 patients with hepatic hemangioma were assigned to the control group.The apparent diffusion coefficient(ADC)values under different b values were compared be-tween the 2 groups;Additionally,draw a receiver operating curve(ROC)to analyze the effectiveness of ADC values in differential diagnosis of hepatocellular carcinoma and hepatic hemangioma under different b values.Results When the result b value was 50 s/mm2,400 s/mm2,and 1000 s/mm2,the ADC values of the observation group were(2.09±0.42),respectively×10-3/mm2/s,(1.72±0.36)×10-3/mm2/s,(1.39±0.28)×10-3/mm2/s,all lower than the control group's(2.45±0.57)×10-3/mm2/s,(2.16±0.45)×10-3/mm2/s,(1.88±0.47)×10-3/mm2/s,with statistical difference(P＜0.05);The ROC results showed that when the b value was 1000 s/mm2,the area under the curve(AUC),sensitivity,and specificity of ADC value for differential diagnosis of hepatocellular carcinoma and hepatic hemangioma were the highest,with values of 0.816,90.70%,and72.70%,re-spectively.Conclusion High field MRI-DWI can effectively differentiate and diagnose hepatocellular carcinoma and hepatic he-mangioma,and the larger the b-value,the stronger the diagnostic effect,which has certain practical value.
关键词
肝细胞癌/肝血管瘤/高场磁共振多b值弥散加权成像/诊断Key words
Hepatocellular carcinoma/Hepatic hemangioma/High field magnetic resonance multi b-value diffusion weighted imaging/Diagnosis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据