Clinical Observation of Early Continuous Blood Purification Treatment for Gastric Canc-er Complicated with Acute Kidney Injury After Operation
Objective To investigate the clinical effect of early continuous blood purification(CBP)in the treatment of postoperative acute kidney injury(AKI)for gastric cancer.Methods According to random number table method,60 gastric canc-er patients with postoperative AKI were divided into the study group(n=30)and reference group(n=30).The former received early CBP treatment,and the latter received traditional CBP treatment.Inflammatory indexes,renal function indexes,severity of disease and length of hospital stay were compared between the 2 groups.Results After treatment,the values of interleukin-6(IL-6),interleukin-8(IL-8)and C-reactive protein(CRP)in the 2 groups were lower than before treatment,while those in the study group were lower than those in the reference group(P＜0.05).After treatment,the values of liver fatty acid-binding protein(L-FABP),renal injury molecule 1(KIM-1)and urine neutrophil gelatinase-associated lipid carrier protein(NGAL)in 2 groups were lower than before treatment,while those in the study group were lower than those in the reference group(P＜0.05).After treat-ment,the acute physiology and chronic health status score Ⅱ(APACHEⅡ)scores of the 2 groups were lower than before treat-ment,while the APACHEⅡscores of the study group were lower than that of the reference group,and the hospital stay was shorter than that of the reference group(P＜0.05).Conclusion Early CBP treatment of gastric cancer complicated with AKI can better reduce inflammatory response,improve renal function,alleviate the disease of patients,shorten the length of hospital stay.
NETL
NSTL
万方数据
