Risk Factor Analysis of Pulmonary Embolism in Patients with Malignant Tumors Com-plicated with Lower Extremity Deep Vein Thrombosis
Objective To explore the risk factors of pulmonary embolism(PE)in malignant tumor with lower limb deep venous thrombosis(DVT).Methods The clinical data of 124 patients with malignant tumor complicated with deep venous throm-bosis of lower limbs were analyzed retrospectively.Results A total of 124 patients were enrolled in this cohort,of which 19 pa-tients(15.3%)in the observation group were complicated with PE,and 105 patients without PE were enrolled in the control group.There was a significant difference in the side of thrombus in lower extremity DVT between the 2 groups(P=0.030).Multi-variate Logistic regression analysis showed that only in-hospital chemotherapy(chemotherapy vs.no chemotherapy,OR=3.495(95%CI:1.081～11.304,P=0.037))was an independent risk factor for PE in malignant tumor patients with lower limb DVT.Conclusion Chemotherapy during hospitalization is a significant risk factor for PE in malignant tumor patients with lower limb DVT,and more active CTPA screening and early intervention are necessary.
Lower extremity deep vein thrombosisMalignancyPulmonary embolismRisk factors
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万方数据
