真菌感染发病率逐年增高,特别是儿童侵袭性真菌病(IFDs)可引起高死亡率,尽早并准确做出真菌感染诊断对降低病死率至关重要。真菌感染的诊断,特别是IFDs的诊断,仍基于三大要素:宿主因素、临床证据(特别是影像学表现)及真菌病原学依据。为加强儿童真菌病尤其是IFDs诊断的理解,现就其诊断进展进行阐述,以提高临床医务人员诊断真菌病的能力。 The morbidity of fungal infections increased year by year。Notably, the invasive fungal diseases (IFDs) in children lead to a high mortality。It is important to make the diagnosis of IFDs in early stage, thus reducing the mortality。The diagnosis of fungal infection is based on three factors, including host factors, clinical evidences (such as imaging findings) and the evidence of fungal etiology。This review described the progress in the diagnosis of IFDs in children, thus improving the ability of physicians to diagnose the fungal infection。
Progress in the diagnosis of fungal infections in children
The morbidity of fungal infections increased year by year.Notably, the invasive fungal diseases (IFDs) in children lead to a high mortality.It is important to make the diagnosis of IFDs in early stage, thus reducing the mortality.The diagnosis of fungal infection is based on three factors, including host factors, clinical evidences (such as imaging findings) and the evidence of fungal etiology.This review described the progress in the diagnosis of IFDs in children, thus improving the ability of physicians to diagnose the fungal infection.