脓毒症的本质是宿主对感染性因素的反应失调而引起的器官功能障碍综合征,其发病率及死亡率居高不下,严重威胁儿童的健康和生命。随着2019年新型冠状病毒的暴发流行,病毒性脓毒症,尤其是呼吸道病毒脓毒症引起广泛关注。尽早确立诊断并及时干预对改善预后大有裨益。因此,现主要围绕儿童呼吸道病毒脓毒症的流行病学、病理生理、诊断及治疗方案进行综述,为临床提供参考。 Sepsis, whose morbidity and mortality remain high in children, is a life-threatening organ dysfunction resulting from dysregulated host responses to infection。With the global outbreak of Corona Virus Disease 2019, viral sepsis, especially respiratory viral sepsis, has attracted much attention。Early diagnosis and timely intervention are of great benefit to improve the prognosis of patients。This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of respiratory viral sepsis in children to provide clinical reference。
Progress in diagnosis and treatment of respiratory viral sepsis in children
Sepsis, whose morbidity and mortality remain high in children, is a life-threatening organ dysfunction resulting from dysregulated host responses to infection.With the global outbreak of Corona Virus Disease 2019, viral sepsis, especially respiratory viral sepsis, has attracted much attention.Early diagnosis and timely intervention are of great benefit to improve the prognosis of patients.This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of respiratory viral sepsis in children to provide clinical reference.