Research progress on susceptibility genes in children with tic disorder
Tic disorder(TD)is a neurodevelopmental disorder that starts in childhood with tics as its primary clinical manifestation.It is a group of movement disorders with unknown causes.At present,the main pathogenic genes of TD have not been identified.In this paper,TD neurotransmitter-associated susceptibility genes(DRD2,DRD4,SLC6A4,HDC,ADRA2A),related susceptibility gene variations(ASH1L,CELSR3,PNKD,NRXN1,CNTN6),and other susceptibility genes(FLT3,SLITRKI)were reviewed to provide references for the precision treatment based on gene variations.
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