Focus on invasive Group A Streptococcal diseases and their risk factors based on a typical case
Group A Streptococci(GAS)can cause multiple diseases such as pharyngotonsillitis,scarlet fever,streptococcal toxic shock syndrome(STSS),necrotizing fasciitis,and so on,making it extremely difficult to monitor all GAS infections.Developed countries such as the United States and the United Kingdom have classified invasive GAS diseases/infections(iGAS)or certain specific types,such as STSS,as notifiable diseases.China only includes scarlet fever caused by GAS infections in the legal infectious diseases.Although case reports or clinical studies of STSS and necrotizing fasciitis in China can be found,there is a lack of investigation and summary on iGAS,and there are few materials to introduce its definition and diagnostic criteria.Based on a recently diagnosed typical case,this paper intends to introduce the definition and diagnostic criteria of iGAS adopted in the United States,the United Kingdom and other developed countries,as well as the valuable early manifestations and risk factors,and the incidence of iGAS.Given the epidemiological changes in GAS infections in recent years,this paper also emphasizes the importance of paying attention to GAS infections,especially iGAS,aiming to arouse the attention of China's clinical doctors and urge them to carry out research on this group of diseases.
ChildRisk factorEpidemiologyGroup A StreptococcusInvasive Group A Streptococcus disease
NETL
NSTL
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