摘要
呼吸道合胞病毒(RSV)是全球范围内5岁以下儿童最常见的呼吸道感染病原体之一,严重威胁儿童健康.近年来RSV感染相关疾病领域研究取得较大进展,为了更好地指导和规范我国儿童RSV感染临床诊疗决策,提升我国儿童的防控水平,特组织儿童呼吸、感染、新生儿、保健、临床流行病学、卫生统计学、病毒学、循证医学、卫生经济学等相关领域专家成立指南制定小组,遵循临床实践指南构建方法学,从临床实践角度提出RSV感染相关检测、诊断、治疗、预防等方面的12个临床问题,通过问题构建、证据检索评价及推荐意见讨论,最终制订"中国儿童呼吸道合胞病毒感染诊疗及预防指南(2024医生版)",以提升我国儿童RSV感染相关疾病的临床诊疗及防控能力.
Abstract
Respiratory syncytial virus(RSV)is one of the most common respiratory pathogens affecting children under 5 years old worldwide,posing a significant threat to their health.In recent years,substantial progress has been made in the field of RSV-related diseases.In order to guide and standardize the clinical decision-making process for RSV diagnosis and treatment and to enhance the prevention and control of RSV infections among children,a guideline development committee has been formed.This committee comprises experts in pediatric respiratory diseases,infectious diseases,neonatology,healthcare,clinical epidemiology,health statistics,virology,evidence-based medicine,and health economics.Following the methodology of constructing clinical practice guidelines,12 clinical questions associating with the detection,diagnosis,treatment,and prevention of RSV-related diseases were proposed from a clinical practice perspective.Through these questions construction,evidence retrieval evaluation,and recommendation opinion discussion,the"Chinese pediatric guideline for diagnosis,treatment,and prevention of respiratory syncytial virus infection(medical version,2024)"were finally formulated to enhance the clinical management and control capabilities of RSV infection related diseases in Chinese children.
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