人工胰腺治疗儿童1型糖尿病的应用现状
Application of artificial pancreas in treatment of type 1 diabetes mellitus in children
杨立红 1徐海 2韩林岐 3魏志强 2孙妍4
作者信息
- 1. 山东第一医科大学(山东省医学科学院)儿科学,济南 250021;山东第一医科大学附属省立医院儿科,济南 250021
- 2. 山东第二医科大学临床医学院,潍坊 261053
- 3. 山东中医药大学中医儿科学,济南 250355
- 4. 山东第一医科大学附属省立医院儿科,济南 250021
- 折叠
摘要
1型糖尿病(T1DM)是儿童糖尿病的主要类型,严重危害儿童健康.随着科技的发展,人工胰腺的出现为T1DM的治疗带来了新的曙光.人工胰腺是通过连续血糖监测、控制算法精准调控胰岛素泵输注,模拟人体胰腺β细胞胰岛素的生理分泌来控制血糖、实现闭环管理.现就人工胰腺目前应用的安全性、有效性、局限性进行综述,以期为T1DM儿童的治疗提供与时俱进的选择.
Abstract
Type 1 diabetes mellitus(T1DM)is the main type of diabetes in children,which seriously endangers children's health.With the development of technology,the emergence of artificial pancreas has brought new progress for the treatment of T1DM.Artificial pancreas can imitate the insulin physiological secretion of pancreas β cells to control glucose,and achieve close-loop management by accurately regulating insulin infusion through continuous glucose monitoring,insulin pump and control algorithms.Here the current clinical studies on the safety,effectiveness and limitations of artificial pancreas in the treatment of T1 DM were reviewed.It is expected to provide another choice for children with T1DM.
关键词
1型糖尿病/儿童/人工胰腺Key words
Type 1 diabetes mellitus/Child/Artificial pancreas引用本文复制引用
基金项目
山东省自然科学基金面上项目(ZR2020MH003)
山东省中医药科技面上项目(M-2022203)
出版年
2024
NETL
NSTL
万方数据