Research progress on relative surgical indications and surgical timing for necrotizing enterocolitis of newborn
Necrotizing enterocolitis(NEC)is a disease that seriously threatens the life of newborns.Its pathogenesis is related to various factors such as gestational age,birth weight,hypoxia,infection,etc.For patients who require surgical treatment,the timing of surgery has an important impact on outcomes.Intestinal perforation has become the consensus of most scholars as an absolute surgical indication for NEC.The relative indications for surgery are still controversial,and therefore,it has become a current NEC research hotspot.Most clinicians judge the timing of surgery based on experience.Non-quantitative evaluation often leads to premature or late timing of surgery,which is not conducive to improving patient outcomes.This article reviews the relative surgical indications and surgical timing assessment for NEC,including surgical timing prediction scores,imaging X-ray examinations,abdominal ultrasonography,infrared spectroscopy,laboratory tests,and NEC surgery prediction models,in order to provide a basis for improving clinical decision-making.