Objetive To investigate the clinical effect of continuous stitching and burying suture in pterygium excision and limbal stem cell transplantation.Methods 70 patients with primary pterygium were randomly divided into observation group and control group.Both groups were treated with modified pterygium excision combined with limbal stem cell transplantation,in which the control group was sutured with conventional interrupted suture,and the observation group was sutured with continuous stitching and burying suture method.Pain score,ocular surface sign score,breaking up time,complications and recurrence rate of the two groups were observed and compared.Results(1)Pain score:There was no significant difference between the two groups at 6 hours after operation(Z=-0.314,P=0.754).The score of the observation group was lower than that of the control group on the 1st and 2nd day after surgery,and the difference was statistically significant(Z1st=-2.842,P1st=0.004;Z2nd=-2.403,P2nd=0.016).(2)Ocular surface sign score:The observation group was superior to the control group on 1st and 2nd day after surgery,and the differences were statistically significant(Z1st=-2.446,P1st=0.014;Z2nd=-2.526,P2nd=0.012).However,there was no statistical difference between the two groups at 1 week after surgery(Z=-1.358,P=0.175).(3)Breaking up time:The breaking up time in the observation group was better than that in the control group one week after operation,and the difference was statistically significant(t=2.135,P=0.036).However,there was no significant difference in breaking up time between the two groups at 4 weeks after surgery(t=0.989,P=0.326).(4)Complications:The scores of the observation group were better than those of the control group 4 weeks and 3 months after surgery,and the differences were statistically significant(Z4w=-2.019,P4w=0.044;Z3mon=-2.945,P3mon=0.003).(5)Recurrence rate:There was no significant difference in recurrence rate between the two groups(P=0.607).Conclusions The continuous stitching and burying suture was used in pterygium excisions and limbal stem cell transplantation can relieve postoperative ocular irritation symptoms,reduce ocular surface inflammation and promote ocular surface reconstruction.
关键词
翼状胬肉/角膜缘干细胞移植术/连续缝合埋线法
Key words
Pterygium/Corneal limbal stem cell transplantation/Continuous stitching and burying suture
维普
万方数据