摘要
目的 分析应用0.01%阿托品滴眼液对青少年近视防控疗效观察.方法 选取本院眼科门诊进行治疗的青少年近视患者(2020年1月至2022年7月)74例作为观察对象,分别是初中组39例(平均年龄13.6岁),高中组35例(平均年龄16.3岁),每组随机分配法对患者进行分组,组别名称为框架镜组及观察组,观察组给予0.01%阿托品滴眼液治疗,框架镜组实施玻璃酸钠滴眼液点滴,都是每天一次睡前点滴.将治疗前后眼轴长度、轴差,治疗前后屈光度及屈光差作为观察指标结合进行治疗效果判定.结果 初中组的框架镜和阿托品治疗一年后轴长分别增加0.91±0.23(mm)、0.38±0.21(mm),(t=1.8612,P<0.05),高中组的框架镜和阿托品治疗一年后轴长分别增加0.68±0.22(mm)、0.25±0.26(mm),(t=1.5612,P<0.05),两组中患者治疗前眼轴长度差异明显,有统计学意义(P<0.05),初中、高中两组患者眼轴长度均有所增加,初中组眼轴长增长相比高中组大,但在使用0.01%阿托品滴眼液干预后,初中生组眼轴长度增长速度的下降幅度显著大于高中生组.结论 应用0.01%阿托品滴眼液对于近视防控的疗效显著,不同年龄段学生在使用0.01%阿托品滴眼液干预后的疗效存在差异,初中生的眼轴长度增长速度相对较快,但使用0.01%阿托品滴眼液后的疗效表现出比高中组较明显的改善,值得在近视防控治疗中应用.
Abstract
Objective To analyze the efficacy of 0.01%atropine preparation in the prevention and control of myopia in teenagers.Method A total of 74 adolescent myopia patients(from January 2020 to July2022)who received treatment in the ophthalmology department of our hospital were selected as observation objects,including 39 cases(average age 13.6 years)in the junior middle school group and 35 cases(average age 16.3 years)in the senior high school group.Each group was randomly assigned to be divided into two groups named the frame mirror group and the observation group,and the observation group was given 0.01%atropine treatment The frame lens group was given sodium hyaluronate eye drops,both of groups were dropped once time a day before bedtime.Axial length、axial difference、diopter and diopter difference before and after treatment were taken as observation indexes to determine the therapeutic effect.Results After one year of treatment with spectacle lenses and atropine,the axial length of the junior high school group increased by 0.91±0.23(mm)and 0.38±0.21(mm)(t=1.8612,P<0.05)respectively.In the high school group,the axial length of spectacle lenses and atropine increased by 0.68±0.22(mm)and 0.25±0.26(mm)(t=1.5612,P<0.05).The difference in axial length between the two groups before treatment was significant and statistically significant(P<0.05).The axial length of the middle school and high school patients increased and the axial length of the middle school group was compared with the high school group.However,after the intervention of 0.01%atropine the growth rate of the axial length of the middle school students decreased significantly,more than that of the high school students.Conclusions The application of 0.01%atropine has a signifcant effect on the prevention and control of myopia,and there are differences in the efficacy of 0.01%atropine in students of different ages after intervention.The axial length of the eyes of junior high school students increases relatively fast,but the efficacy of 0.01%atropine shows a more obvious improvement than that of the senior high school group,which is worthy of application in the prevention and control treatment of myopia