Objective To evaluate the correlation between force alignment and ankle coronal alignment in preoperative knee varus deformity,as well as the alteration in ankle coronal alignment subsequent to unicompartmental knee arthroplasty(UKA)among patients with knee varus deformity.Methods 42 patients who underwent UKA between 2021 and 2022 were selected,including 5 males and 37 females,aged 49~73 years,mean age(61.45±6.60)years.The force lines and angles of the upper knee and ankle joint were measured on full-length DR films of both lower limbs(in weight-bearing position)before and after the surgery.The angles measured encompassed the hip-knee-ankle angle(HKA),medial proximal tibial angle(MPTA),tibial anterior surface angle(TAS),tibial plateau inclination(TPI),talar inclination(TI),and tibiotalar tilt(TT).Results All 42 patients were followed 10~14 months,with an average of(12.3±1.7)months.The average correction angle of knee varus deformity was(5.34±2.61)°.The MPTA changed from(83.41±1.44)° before operation to(88.06±0.93)° after;TAS changed from(89.14±4.12)° to 8(7.92±3.87)°;and TPI and TI changed from 93.08 ° and 91.58 ° to 89.38 ° and 88.86 °,respectively(P<0.05).There was a significant correlation between HKA and MPTA,TPI,TI before operation(P<0.05),suggesting that knee varus deformity affects the tilt of the distal ankle joint preoperatively.Additionally,there was a significant correlation between HKA,MPTA,and TPI after UKA(P<0.05),indicating that ankle tilt and misalignment changed with the correction of the lower limb force line post-UKA.Conclusion The alignment of the ankle joint is affected to a certain extent by knee varus deformity.UKA can improve the malalignment and alignment of the distal ankle joint by correcting knee varus deformity,which has a positive impact on maintaining the stability of the ankle joint.