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糖尿病踝关节骨折术后Charcot关节病发生的危险因素分析

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目的 评估手术治疗糖尿病(diabetes mellitus,DM)踝关节骨折的疗效,并分析术后Charcot关节病(Charcot neuroarthropathy,CNO)发生的相关危险因素。方法 回顾分析2019年1月至2023年6月佛山市中医院收治且符合选择标准的127例采用切开复位内固定术治疗的单侧DM踝关节骨折患者。其中男73例,女54例;年龄39~79岁,平均(61。7±8。6)岁。依据随访X线片评估骨折愈合情况,采用Baird-Jackson踝关节评分评估临床疗效,统计随访期间并发症发生情况。并对术后CNO发生相关危险因素进行分析。结果 术后23例出现切口浅表感染及延迟愈合,3例发生深部感染,其余患者切口均一期愈合。随访时间7~19个月,平均(12。2±3。5)个月。109例成功愈合,其中延迟愈合25例,平均愈合时间(3。4±0。5)个月;骨折不愈合18例,其中内固定断裂9例。12例发生CNO,115例未发生CNO。临床疗效方面,优89例,良12例,可8例,差18例,优良率79。5%。单因素分析示,两组间DM病程、周围神经病变、糖化血红蛋白水平和DM慢性并发症比较差异有统计学意义;进一步行logistic回归分析示,周围神经病变和DM慢性并发症是DM踝关节骨折术后CNO发生的危险因素。结论 手术治疗DM踝关节骨折总体疗效满意,但术后并发症发生率较高,合并周围神经病变和DM慢性并发症时CNO发生风险将增加。
Risk Factors for Charcot Arthropathy After Diabetic Ankle Fracture Surgery
Objective To evaluate the outcome of surgical treatment for diabetic ankle fractures and analyze the risk factors for postoperative Charcot neuroarthropathy(CNO).Methods A retrospective analysis was performed on 127 patients with unilateral diabetes mellitus(DM)ankle fractures who were treated with open reduction and internal fixation in Foshan Hospital of Traditional Chinese Medicine from January 2019 to June 2023 and met the selection criteria.There were 73 males and 54 females with an average age of(61.7±8.6)years old,ranging from 39 to 79 years old.Fracture healing was evaluated by follow-up X-rays,and the Baird-Jackson ankle score was used to evaluate clinical efficacy.The incidence of complications during the follow-up period was recorded,and the risk factors for postoperative CNO were analyzed.Results Postoperatively,23 cases had superficial infection and delayed healing of the incision,3 cases had deep infection,and the incisions of the remaining patients healed by primary intention.The follow-up time was 7~19 months,with an average of(12.2±3.5)months.109 cases healed successfully,25 cases had delayed healing,with an average healing time of(3.4±0.5)months;18 cases had nonunion,and 9 cases had internal fixation fracture;12 cases had CNO,and 115 cases did not have CNO.In terms of clinical efficacy,89 cases were excellent,12 cases were good,8 cases were fair,and 18 cases were poor,with an excellent and good rate of 79.5%.Univariate analysis showed that there were significant differences in DM course,peripheral neuropathy,glycosylated hemoglobin level and chronic complications of DM between the two groups;further logistic regression analysis showed that peripheral neuropathy and chronic complications of DM were risk factors for CNO after DM ankle fracture surgery.Conclusion The overall outcome of surgical treatment for diabetic ankle fractures is satisfactory;however,the incidence of postoperative complications is high.The risk of CNO increases when there is a concomitant presence of diabetic peripheral neuropathy and chronic diabetes complications.

diabetes mellitusankle fractureCharcot neuroarthropathyrisk factors

张凯亭、黄圣含、邹保利、莫方东、邹运璇、揭珂、张宏宁、朱永展

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广州中医药大学第八临床医学院,广东 广州 510006

佛山市中医院足踝外科,广东佛山 528051

糖尿病 踝关节骨折 Charcot关节病 危险因素

2024

实用骨科杂志
中华医学会山西分会,北京大学第三医院

实用骨科杂志

CSTPCD
影响因子:1.239
ISSN:1008-5572
年,卷(期):2024.30(12)