临床输血检验中不规则抗体检验的应用
Application of irregular antibody test in clinical blood transfusion examination
张文杰1
作者信息
- 1. 273300 山东临沂,平邑县人民医院输血科
- 折叠
摘要
目的 探讨临床输血检验中不规则抗体检验的应用价值.方法 选择2022年6月—2023年6 月平邑县人民医院收治的 2260 例输血治疗患者作为研究对象,所有患者输血前均接受不规则抗体检验,统计输血不良反应发生率,分析不规则抗体检出情况及阳性分型.结果 2260 例输血患者中检出不规则抗体阳性40例,阳性检出率为1.77%,其中抗-M分型29例,占比最高,可达72.50%,其次是抗-E分型5例,占比为 12.50%;输血不良反应发生率为 1.02%(23/2260).女性、有妊娠史女性、有输血史人群的不规则抗体阳性检出率[分别为 2.55%(28/1098)、3.53%(21/1595)、3.24%(29/895)]均明显高于男性、无妊娠史女性和无输血史人群[分别为 1.03%(12/1162)、1.39%(7/503)、0.81%(11/1365)],差异均有统计学意义(均P<0.05).结论 在临床输血前实施不规则抗体检验意义重大,可准确检出不规则抗体,保证输血治疗的安全性,避免严重输血反应发生.
Abstract
Objective To investigate the application value of irregular antibody test in clinical blood transfusion examination.Methods The 2260 patients admitted in Pingyi County People's Hospital undergoing blood transfusion treatment were selected as research objects,with a time range of June 2022 to June 2023.All selected patients underwent irregular antibody test before blood transfusion,and the incidence of adverse reactions during blood transfusion was analyzed.The detection and positive typing of irregular antibodies were also analyzed.Results Out of 2260 patients with blood transfusion,40 cases were found to be positive for irregular antibodies,with a positive detectable rate of 1.77%.Among them,the highest proportion was anti-M typing(29 cases),accounting for 72.50%,followed by anti-E typing(5 cases),accounting for 12.50%.The incidence of adverse blood transfusion reactions in the selected patients was 1.02%(23/2260).The positive detectable rates of irregular antibodies in female,women with a history of pregnancy and those with a history of blood transfusion[2.55%(28/1098),3.53%(21/1595)and 3.24%(29/895),respectively]were significantly higher than those in male,women without a history of pregnancy and those without a history of blood transfusion[1.03%(12/1162),1.39%(7/503)and 0.81%(11/1365),respectively],and the differences were statistically significant(all P＜0.05).Conclusion Implementing irregular antibody test before clinical blood transfusion is of great significance,as it could accurately detect irregular antibodies,ensure the safety of blood transfusion treatment,and avoid serious transfusion reactions.
关键词
输血/不规则抗体检验/抗体阳性率/输血不良反应Key words
Blood transfusion/Irregular antibody test/Antibody positivity rate/Adverse blood transfusion reaction引用本文复制引用
出版年
2024
NETL
NSTL
万方数据