Sepsis is one of the common infectious diseases in emergency department and intensive care unit.It usually has different infection routes,such as respiratory tract,urinary tract and so on.Sepsis usually directly or indirectly causes different organ function damage,acute kidney injury(AKI)is one of the most common complications of sepsis.Usually,kidney injury was identified according to the patient's urine output and creatinine(Cr)level.However,the identification of kidney injury by urine output and Cr level not only has a hysteresis effect,but also the decrease of urine output and the increase of Cr level do not participate in the occurrence of kidney injury.Therefore,it is particularly important to find biomarkers or other diagnostic methods that could accurately identify the occurrence of kidney injury by understanding the mechanism of sepsis.This article reviews the mechanisms and early diagnosis methods of sepsis related acute kidney injury(SAKI).
关键词
脓毒症/脓毒症相关急性肾损伤/生物标志物/早期诊断
Key words
Sepsis/Sepsis related acute kidney injury/Biomarker/Early diagnosis
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