Omics is a broad and popular area in biomedical research.There is considerable evidence demonstrating that translation procedures and holistic analysis methods in omics could enrich laboratory diagnostics and improve clinical outcomes.Metabolomics involves the study of metabolites in living organisms,primarily focusing on molecules with low molecular weight.These molecules could be either endogenous metabolites or exogenous,and could reflect environmental factors such as diet,microbial activity and medication.Targeted metabolomics is a valuable tool employed in clinical screening,diagnosis,prognosis and routine clinical assessments.Non-targeted metabolomics is a data-driven,hypothesis-generating approach that involves the comprehensive analysis of a wide array of metabolites.The application of biomarkers in diagnosis,monitoring and implementation of precision medicine and individualized clinical interventions for critically ill patients could improve prognosis.The advancement of metabolomics has potential to enhance medical treatment and healthcare across various clinical disciplines.
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