实用检验医师杂志2024,Vol.16Issue(3) :219-221.DOI:10.3969/j.issn.1674-7151.2024.03.007

中性粒细胞与淋巴细胞比值对急性心肌梗死后院内心源性休克的预测价值

Predictive value of neutrophil to lymphocyte ratio for nosocomial cardiogenic shock after acute myocardial infarction

陈宏飞 魏权 刘颖
实用检验医师杂志2024,Vol.16Issue(3) :219-221.DOI:10.3969/j.issn.1674-7151.2024.03.007

中性粒细胞与淋巴细胞比值对急性心肌梗死后院内心源性休克的预测价值

Predictive value of neutrophil to lymphocyte ratio for nosocomial cardiogenic shock after acute myocardial infarction

陈宏飞 1魏权 1刘颖1
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作者信息

  • 1. 364000 福建龙岩,龙岩人民医院检验科
  • 折叠

摘要

目的 探讨中性粒细胞与淋巴细胞比值(NLR)对急性心肌梗死(AMI)后院内心源性休克(CS)的预测价值.方法 回顾并分析 2021 年 1 月—2023 年 10 月龙岩人民医院收治的 100 例AMI患者的临床资料;将梗死后出现院内CS的 55 例患者纳入休克组,未出现CS的 45 例患者纳入未休克组,根据休克指数(SI)将休克组患者分为轻度休克组(30 例)和中重度休克组(25 例).采用全自动血细胞分析仪检测中性粒细胞计数(NEU)、淋巴细胞计数(LYM),并计算NLR,比较各组上述指标水平差异;绘制受试者工作特征曲线(ROC曲线)并计算ROC曲线下面积(AUC),考察NLR对AMI后院内CS的预测价值.结果 休克组患者的NEU、NLR水平均显著高于未休克组,LYM水平显著低于未休克组[NEU(×109/L):10.35±3.13 比 5.23±2.11;NLR:8.84±6.07 比 4.04±3.43;LYM(×109/L):1.45±0.52 比 1.86±0.75;均P<0.05];中重度休克组的NLR水平显著高于轻度休克组(12.16±7.49 比 6.08±2.18,P<0.05).ROC曲线分析结果显示,NLR预测AMI后院内CS的AUC为 0.848,截断值为 6.055,敏感度为 74.54%,特异度为86.67%,准确度为 80.00%.结论 NLR对AMI后院内CS的预测有一定的参考价值.

Abstract

Objective To explore the predictive value of neutrophil to lymphocyte ratio(NLR)for nosocomial cardiogenic shock(CS)after acute myocardial infarction(AMI).Methods The clinical data of 100 patients with AMI in Longyan People's Hospital from January 2021 to October 2023 were retrospectively analyzed.The 55 patients with in-hospital CS after infarction were included in shock group,and 45 patients without CS were included in non-shock group.According to shock index(SI),the patients in shock group were divided into mild shock group(30 cases)and moderate-severe shock group(25 cases).The levels of neutrophil count(NEU)and lymphocyte count(LYM)were detected using fully automated blood cell analyzer,and NLR was calculated.The levels of above indicators in each group were compared.The receiver operator characteristic curve(ROC curve)was drawn and area under ROC curve(AUC)was calculated to examine the predictive value of NLR for in-hospital CS after AMI.Results The levels of NEU and NLR in shock group were higher than those in non-shock group,while the level of LYM was lower than that in non-shock group[NEU(×109/L):10.35±3.13 vs.5.23±2.11;NLR:8.84±6.07 vs.4.04±3.43;LYM(×109/L):1.45±0.52 vs.1.86±0.75;all P<0.05].The level of NLR in moderate-severe shock group was higher than that in mild shock group(12.16±7.49 vs.6.08±2.18,P<0.05).ROC curve showed that AUC,cut-off value,sensitivity,specificity and accuracy of NLR for predicting nosocomial CS after AMI were 0.848,6.055,74.54%,86.67%and 80.00%,respectively.Conclusion NLR has certain predictive value for nosocomial CS after AMI.

关键词

急性心肌梗死/心源性休克/中性粒细胞/淋巴细胞比值

Key words

Acute myocardial infarction/Cardiogenic shock/Neutrophil to lymphocyte ratio

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出版年

2024
实用检验医师杂志
中国医师协会 天津市天津医院

实用检验医师杂志

影响因子:0.297
ISSN:1674-7151
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