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玫瑰痤疮277例甲状腺功能分析

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目的 分析玫瑰痤疮患者甲状腺功能(以下简称甲功)的临床特征,探讨玫瑰痤疮患者的甲功特点.方法 收集2019年7月至2022年7月在新疆维吾尔自治区人民医院门诊及住院的玫瑰痤疮患者277例(病例组)及同期在该院体检中心体检的健康人群280例(对照组)作为研究对象.2组性别、年龄比较差异无统计学意义(P>0.05),具有可比性.收集2组所有研究对象的一般资料和甲功相关指标水平等数据,并对相关因素进行统计分析.结果 ①2组患者甲功中血清游离三碘甲状腺原氨酸(FT3)、三碘甲状腺原氨酸(T3)、促甲状腺激素(TSH)水平比较差异均有统计学意义(P<0.05),而游离甲状腺素(FT4)、甲状腺素(T4)、抗甲状腺过氧化物酶(TPO)和抗甲状腺球蛋白(TGAb)抗体水平比较差异均无统计学意义(P>0.05);②对不同病情严重程度的玫瑰痤疮患者的甲功指标进行比较,结果提示轻、中、重度玫瑰痤疮患者各项甲功指标比较差异无统计学意义(P>0.05);③2组患者甲状腺超声甲状腺大小比较差异无统计学意义(P>0.05),轻、中、重度玫瑰痤疮患者甲状腺大小比较差异也无统计学意义(P>0.05).结论 玫瑰痤疮患者的血清甲功指标水平均在正常范围,FT3、T3、TSH水平与健康人群比较差异有统计学意义(P<0.05).
Thyroid function analysis in 277 patients with rosacea
Objective To investigate the correlation between rosacea and abnormal thyroid function by analyzing the clinical characteristics of thyroid function.Methods A total of 277 rosacea patients from July 2019 to July 2022 in Xinjiang Uygur Autonomous Region Hospital and 280 healthy patients who underwent physical examination in the same hospital were collected as study subjects.No statistically significant differences were observed in terms of sex and age(P>0.05),indicating their comparability.General data and indicators related to thyroid function levels of all study subjects were collected from both groups,followed by a statistical analysis of the related factors.Results The serum levels of free triiodothyronine(FT3),triiodothyronine(T3)and thyroid-stimulating hormone(TSH)differed significantly between the two groups(P<0.05).However,there were no significant differences observed in the levels of free thyroxine(FT4),thyroxine(T4),anti-thyroid peroxidase(TPO)and anti-thyroglobulin(TGAb)antibodies between the two groups(P>0.05).The indicators in patients with rosacea of different severity were also compared,and the results suggested that there was no significant difference in thyroid function(P>0.05).Moreover,the comparison of thyroid size between the observation group and the control group in thyroid ultrasound did not show statistically significant differences(P>0.05).The comparison of thyroid size between the mild and severe rosacea groups was also not statistically significant(P>0.05).Conclusion The serum thyrofunction indexes in rosacea patients were within the normal range,while the levels of FT3,T3,and TSH exhibited significant differences compared to those of healthy individuals.

RosaceaThyroid functionThyroid hormoneThyroid autoantibody

向芳、马云霞、朱学娥、丁媛、康晓静

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830001 乌鲁木齐,新疆维吾尔自治区人民医院皮肤性病科,新疆皮肤病临床医学研究中心,新疆皮肤病研究重点实验室

玫瑰痤疮 甲状腺功能 甲状腺激素 甲状腺自身抗体

2024

实用皮肤病学杂志
中国人民解放军北京军区总医院

实用皮肤病学杂志

CSTPCD
影响因子:0.637
ISSN:1674-1293
年,卷(期):2024.17(1)
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