日光性角化病治疗研究进展
Research progress on the treatment of actinic keratosis
何璐 1李东霞1
作者信息
- 1. 010000 呼和浩特,内蒙古医科大学附属医院皮肤科
- 折叠
摘要
日光性角化病(actinic keratosis,AK)是与紫外线照射等因素相关的一种癌前病变,有进展为鳞状细胞癌(squamous cell carcinoma,SCC)的风险.AK好发于曝光部位,且随着年龄的增长,该病发病率呈逐年增长的趋势,需医患双方均应重视,并严格跟踪随访,避免发生癌变.目前现有的防治方法主要有3个方向:病灶靶向治疗,局部定向治疗,生活方式预防.通过对AK的治疗与预防方案的机制与利弊进行综述,旨在为医生与患者提供更有效的选择.
Abstract
Actinic keratosis(AK)is a precancerous lesion associated with factors such as ultraviolet radiation,posing a risk of progression to squamous cell carcinoma(SCC).AK is more prevalent in sun-exposed areas,and with increasing age,the incidence of the disease shows a yearly upward trend.This demands special attention from both doctors and patients,necessitating strict follow-up to prevent the occurrence of cancer.At present,there are three main directions of prevention and treatment methods:lesion-directed therapies;field-directed therapies;lifestyle prevention.This article reviews the mechanisms,pros,and cons of treatment and prevention options for AK,aiming to provide physicians and patients with more effective options.
关键词
角化病,光化性/治疗/光动力治疗/氟尿嘧啶/咪喹莫特Key words
Keratosis,actinic/Therapies/Photodynamic therapy/Fluorouracil(FU)/Imiquimod引用本文复制引用
基金项目
草原英才工程产业创新创业人才团队项目(2018)(02036030)
内蒙古自治区自然科学基金(2020LH08018)
出版年
2024
NETL
NSTL
万方数据