A case of eosinophilic pustular folliculitis misdiagnosed as tinea facialis
A 21-year-old male patient presented with recurrent facial erythema and pustules,along with itching for six months.The dermatological condition showed that the large patches of fused erythema on the face,with a distinct boundary and a tendency to fade in the center.The erythema is scattered with follicular red papules and pustules measuring 1-2 mm in size,without tenderness.The histopathological examination of facial skin biopsy showed that a significant infiltration of eosinophils,along with a minor presence of neutrophils and lymphocytes,was observed surrounding the sebaceous glands of hair follicles,blood vessels,and sweat glands in the superficial middle dermis.Eosinophilic microabscesses were formed within the sebaceous glands of hair follicles,resulting in partial destruction.The patient was diagnosed as eosinophilic pustular folliculitis.The patient received a combination therapy of oral prednisone tablets at a dosage of 20 mg per day along with topical tacrolimus.Gradual tapering of the prednisone was initiated after 5 days,leading to significant improvement in skin lesions after 3 months of treatment.