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儿童线状汗孔角化病1例

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患儿男,4岁,因左上肢、手部线状斑疹6个月就诊.反射式共聚焦显微镜(RCM)检查示界限清楚的低折光隆起,内可见角化不全细胞,基底层色素环完整;真皮乳头内可见灶性的噬色素细胞及炎性细胞浸润.皮肤镜下见多发褐色皮损,边缘堤状隆起,可见双轨征,中央可见角栓.组织病理检查:表皮角化过度伴柱状角化不全,真皮浅层少许噬色素细胞及淋巴细胞浸润,可见角化不全柱,下方棘层变薄.根据RCM、皮肤镜及组织病理检查结果,诊断为儿童线状汗孔角化病.
Linear porokeratosis in child:A case report
The patient,a 4-year-old boy,presented with linear macules on the left upper limb and hand for 6 months.Reflectance confocal microscopy(RCM)examination revealed well-defined,low reflectance elevations with dyskeratotic cells visible within,intact pigment rings in the basal layer.Additionally,focal melanophage and inflammatory cell infiltration within the dermal papilla were observed.Dermoscopy showed multiple brown skin lesions with raised edges,double-track signs,and central keratin plugs.Histopathological examination demonstrated epidermal hyperkeratosis with focal dyskeratosis,mild infiltration of melanophages and lymphocytes in the superficial dermis,and visible dyskeratotic columns with thinning of the spinous layer below.Based on RCM,dermoscopy,and histopathological findings,the patient was diagnosised as linear porokeratosis.

Porokeratosis,linearChildRCMDermoscopy

刘欣欣、毕田田、任敏、李钦峰、宫泽琨

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天津 300074,天津市儿童医院/天津大学儿童医院皮肤科

汗孔角化病,线状 儿童 反射式共聚焦显微镜 皮肤镜

天津市卫生健康委员会科技项目

ZC20077

2024

实用皮肤病学杂志
中国人民解放军北京军区总医院

实用皮肤病学杂志

CSTPCD
影响因子:0.637
ISSN:1674-1293
年,卷(期):2024.17(4)