Clinical efficacy of CT-guided dorsal root ganglion pulsed radiofrequency combined with nerve block in the treatment of postherpetic neuralgia
Objective To investigate the efficacy and safety of CT-guided dorsal root ganglion pulsed radiofrequency(DRG-PRF)combined with nerve block in the treatment of patients with postherpetic neuralgia(PHN).Methods 96 patients with PHN who received treatment at Lujiang County People's Hospital from May 2022 to March 2024 were enrolled in this study,and were divided into combined therapy group and control group by random number table method,with 48 cases in each group.The patients in the combined therapy group were treated with DRG-PRF combined with nerve block,while the control group was given nerve block.The pain degree[visual analogue scale(VAS)],sleep quality[pittsburgh sleep quality index(PSQI)],dosage of oral analgesics and pain sensitivity were compared between groups before treatment and after 1,2,4 and 8 weeks of treatment,and the adverse reactions were observed.Results After 1,2,4 and 8 weeks of treatment,the VAS score,PSQI score,dosage of oral analgesics and pain sensitivity of PHN patients in both groups were significantly decreased(P＜0.05),and these reductions were more pronounced in combined therapy group compared to control group(P＜0.05).There was no obvious difference in the overall incidence rate of adverse reactions between groups(P＞0.05).Conclusion CT-guided DRG-PRF combined with nerve block can effectively relieve the pain,reduce the dosage of analgesic drugs,and improve the sleep quality in the treatment of PHN patients,demonstrating safety and feasibility.
万方数据
维普
