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分子靶向药物治疗难治性环状肉芽肿研究进展

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环状肉芽肿作为非感染性肉芽肿性疾病,有一定的自愈倾向,但在临床中有部分患者迁延不愈且全身泛发,称为难治性环状肉芽肿.环状肉芽肿病因及发病机制不明而治疗困难.近年来,随着分子靶向药物在临床中的普及,给难治性环状肉芽肿的治疗带来了新的思路.该文回顾了近20年难治性环状肉芽肿的分子靶向药物治疗研究状况,探讨其治疗及发病机制新进展.
Advancement in molecular targeted drugs therapy of refractory granuloma annulare
As a non-infectious granulomatous disease,granuloma annulare has a certain tendency to resolve spontaneously.However,some cases persist and become widespread,referred to as refractory granuloma annulare.The etiology and pathogenesis of granuloma annulare remain unclear.In recent years,with the popularity of molecular targeted drugs in clinic practice,the increasing use of molecular targeted therapies in clinical practice has provided new approaches to the treatment of granuloma annulare.

Granuloma annulare,refractoryTargeting preparationMolecular targeted drugs therapy

张鸫媛、张斌、舒虹

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650000 昆明,昆明市儿童医院皮肤科

首都医科大学附属北京儿童医院皮肤科

环形肉芽肿 难治性 靶向制剂 分子靶向治疗

2024

实用皮肤病学杂志
中国人民解放军北京军区总医院

实用皮肤病学杂志

CSTPCD
影响因子:0.637
ISSN:1674-1293
年,卷(期):2024.17(6)