首页|亚急性皮肤型红斑狼疮误诊为寻常型银屑病1例

亚急性皮肤型红斑狼疮误诊为寻常型银屑病1例

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报道1例亚急性皮肤型红斑狼疮误诊为寻常型银屑病.患者女,75岁.躯干、四肢出现鳞屑性红斑和丘疹,伴片状脱发1年余.体格检查:头面部、躯干、四肢可见广泛散在分布甲片大小的红斑、红斑内可见毛囊性丘疹,红斑表面覆有轻薄鳞屑,头皮局部红斑轻度浸润,部分皮损表面可见抓破后的渗血、结痴,表面少量脱屑,无明显渗液、触痛.曾误诊为寻常型银屑病,予以外用糖皮质激素软膏,以及窄谱中波紫外线照射等治疗,效果不佳,持续脱发.经皮肤镜检查和组织病理检查,最终诊断为亚急性皮肤型红斑狼疮.予以硫酸羟氯喹0.2 g每日2次口服,白芍总苷胶囊0.6 g每日3次口服,醋酸泼尼松龙片30 mg每日1次口服(疗程1个月),外用卤米松乳膏每日2次.3个月后随访,躯干鳞屑性红斑大部分消退,遗留少部分色素沉着,原有脱发部位已长出新发.
Subacute cutaneous lupus erythematosus misdiagnosed as psoriasis vulgaris:a case report
A case of subacute cutaneous lupus erythematosus was reported.A 75-year-old female patient presented with scaly erythematous plaques and papules on her trunk and limbs,accompanied by flaky alopecia for over a year.Physical examination revealed widely scattered,erythematous plaques,approximately the size of a fingernail,on the head,face,trunk,and limbs.These plaques contained follicular papules and were covered with thin,light scales.Mild erythematous infiltration was noted on the scalp,with some lesions showing post-scratching blood oozing,crusting,and minimal scale shedding,without obvious exudation or tenderness.The patient was misdiagnosed as psoriasis vulgaris.Limited affection was observed with topical glucocorticoids and NB-UVB therapy.Dermatoscopic examination and histopathological analysis led to a final diagnosis of subacute cutaneous lupus erythematosus.The patient was treated with hydroxychloroquine sulfate 0.2 g twice daily,total glucosides of paeony 0.6 g three times daily,and prednisone acetate 30 mg once daily for 1 month.Topical halometasone cream was applied twice daily.Three months later,follow-up examination showed significant resolution of the scaly erythematous plaques on the trunk,with a small amount of pigmentation remaining,and new hair had grown in the areas of hair loss.

Cutaneous lupus erythematosus,subacutePsoriasis,vulgarisMisdiagnosis

刘承灵、邓涵杰、温海宇、汪俊芳、叶竞辉、杨扬、王丹、张海鹏、杨卫兵、李欣

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541000 桂林,中国人民解放军联勤保障部队第九二四医院皮肤科

中国人民解放军联勤保障部队第九二四医院病理科

皮肤型红斑狼疮,亚急性 银屑病,寻常性 误诊

2024

实用皮肤病学杂志
中国人民解放军北京军区总医院

实用皮肤病学杂志

CSTPCD
影响因子:0.637
ISSN:1674-1293
年,卷(期):2024.17(6)