摘要
目的 分析我国肾移植受者死亡原因及特点.方法 通过中国生物医学文献数据库、中国知网、万方医学网检索系统,以"肾移植""死亡"和"原因"为关键词进行检索,对纳入的 15 篇文献进行统计分析.结果 包含 1977—2018 年的肾移植受者共 18070 例,受者发生死亡 2286 例,死亡发生率为2.0%～35.7%,总体死亡率为 12.6%(2286/18070).受者死亡原因包括感染 810 例(35.4%)、心脑血管疾病787例(34.4)、肝衰竭344例(15.1%)、胃肠道疾病73例(3.2%)、肿瘤69例(3.0%)、意外死亡19例(0.8%)、经济因素 10 例(0.5%)、其他原因 174 例(7.6%).结论 肾移植受者主要死亡原因是感染和心脑血管疾病,次要原因是肝衰竭,少见原因是胃肠道疾病、肿瘤,其他原因罕见.
Abstract
Objective To analyze the causes and characteristics of death of kidney transplant recipients.Methods"Kidney transplantation""death"and"cause"were searched in the retrieval system of China Biomedical Literature Database,China National Knowledge Network and Wanfang Medical network,and the 15 literatures included were statistically analyzed.Results A total of 18070 kidney transplant recipients from 1977 to 2018 were included,and 2286 of them died,with the mortality rate ranging from 2.0%to 35.7%,and the overall mortality rate was 12.6%(2286/18070).The causes of death included 810 cases(35.4%)of infection,787 cases(34.4)of cardiovascular and cerebrovascular diseases,344 cases(15.1%)of liver failure,73 cases(3.2%)of gastrointestinal diseases,69 cases(3.0%)of tumor,19 cases(0.8%)of accidental death,10 cases(0.5%)of economic factors,and 174 cases of other causes(7.6%).Conclusion Infection and cardiovascular and cerebrovascular diseases were the main causes of death in kidney transplant recipients,liver failure was the secondary cause,and gastrointestinal diseases and tumors were the rare causes,and other causes were rare.
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