Objective To explore the application of two optimization methods in Monaco system under intensity modula-ted radiation therapy(DMLC)and volumetric modulated arc therapy(VMAT)in cervical cancer.Methods A total of 40 patients with cervical cancer who received intensity-modulated radiotherapy in Cangzhou People's Hospital from Janu-ary 2020 to December 2022 were selected.After IMRT and VMAT,the effects of the two modes were analyzed.Results Under Constrained Mode,Dmean[(5 225.41±32.53)cGy vs.(5 205.84±32.99)cGy],Dmax[(5 585.46±51.64)cGy vs.(5 635.99±62.12)cGy],bladder V20[(78.07±6.31)％vs.(85.68±9.42)％],rectal V20[(87.58± 6.14)％vs.(88.75±5.21)％],rectal V40[(34.21±6.71)％vs.(37.77±5.41)％],pelvis V20[(84.74±4.91)％vs.(82.18±4.78)％],pelvis V30[(51.77±6.73)％vs.(54.73±6.02)％],left femoral head V20[(42.16± 8.40)％vs.(37.37±8.68)％],right femoral head V30[(9.90±3.43)％vs.(12.32±4.46)％]dose,the differences were significant(P＜0.05).Under the DMLC emphasis,the number of machine jumps in Constrained mode was lower than that in Pareto mode(P＜0.05),under the VMAT emphasis,the number of Pareto mode subfields was lower than that in Constrained mode(P＜0.05),and the number of machine jumps was higher than that in Constrained mode(P＜0.05).Conclusion VMAT technology can meet the radiation requirements of cervical cancer patients,and Pareto mode is better for endangering organ protection.
维普
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