A comparative study on the effect of different anesthesia methods on early postoperative inflammatory indicators and rehabilitation in patients undergoing cesarean section
Objective To evaluate the effects of different anaesthetic methods on inflammatory markers and rehabilitation after.caesarean section,and provide a reference for the selection of anaesthetic methods for caesarean section surgery.Methods A total of 1 759 patients undergoing emergency caesarean section in the Southern District of the First Affiliated Hospital of the University of Science and Technology of China from January 2022 to May 2023 were divided into general anaesthesia group(group G,n=200)and epidural anaesthesia group(group E,n=1 559).The parturients were select-ed according to specific inclusion and exclusion criteria,and then the parturients in the two groups were matched in a 1:1 ratio using the propensity score method.The effects of two different anaesthetic methods on white blood cell(WBC),platelet to lymphocyte ratio(PLR),neutrophil to lymphocyte ratio(NLR),monocyte to lymphocyte ratio(MLR)and postoperative rehabilitation were compared.Results WBC,NLR and MLR in group E were significantly higher than those before surgery,while WBC,PLR,NLR and MLR in group G were significantly higher than those before surgery.Compared with group E,the difference of PLR before and after surgery in group G[16.78(0.16,29.36)vs.-2.20(-21.69,15.17)]was significantly higher(P＜0.05).In group G,the time from induction of anaesthesia to fe-tal delivery[6(3,12)min vs.43(32,54)min]and the time from skin incision to fetal delivery[3(2,7)min vs.7(6,12)min]were significantly shortened,whereas the postoperative farting time[44(39,46)h vs.39(36,43)h]was significantly longer(P＜0.05).At 5 minutes before skin incision and during skin incision,group E had signifi-cantly lower MAP and HR compared to group G(P＜0.05).There were no significant differences in intraoperative blood loss and postoperative hospital stay between the two groups(P＞0.05).Conclusion Epidural anaesthesia may be more beneficial for the mother's recovery,while general anaesthesia is appropriate for emergency delivery of the fetus.
Cesarean sectionMethods of anesthesiaPlatelet to lymphocyte ratioNeutrophil to lymphocyte ratioMon-ocyte to lymphocyte ratio
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