Objective To observe the effect of moxibustion therapy on the level of inflammatory factors and the traditional Chinese medicine(TCM)syndrome scores and clinical efficacy on gastrointestinal dysfunction in patients with uremia.Methods Selected 72 cases of gastrointestinal dysfunction in patients with uremia in Putuo Hospital of Shanghai University of Traditional Chinese Medicine and Jinshan District Central Hospital Affiliated to Shanghai University of Medicine & Health Sciences from May 2021 to January 2022.The patients were divided into a moxibustion group(n=36)and a control group(n=36)by randomized numerical table method.The control group received basic treatment(continuous peritoneal dialysis,antihypertensive therapy,control of blood glucose,support nutritional intake,inhibition of the secretion of stomach acid,improvement of gastrointestinal motility,and other symptomatic treatment).The moxibustion group was supplemented by moxibustion at Zusanli and Sanyin jiao acupoint on the based on the control group.Safety indicators,serum tests for inflam-matory factors(CRP,TNF-α,IL-6),and TCM symptomatic efficacy results were collected from patients before and after 1 week of treatment.Results Three cases were dislodged during the observation period(2 cases were transferred to hemodi-alysis treatment and 1 case withdrew),and 69 cases were completed(35 cases in the control group and 34 cases in the moxibustion group).The effective rate of treating gastrointestinal dysfunction in uremia was significantly higher than that of the control group(P＜0.05).The serum CRP,TNF-α,and IL-6 in the moxibustion group and the control group were lower than those before treatment,and the moxibustion group were lower than the cotrol group(P＜0.01).The total effective rate of the treatment of the TCM syndrome in the moxibustion group was(88.24％,30/34),which was significantly higher than that in the control group(65.71％,23/35,x2=4.911,P=0.027).Conclusion Moxibustion therapy can significantly reduce the levels of inflammatory factors IL-6,TNF-α,and CRP on gastrointestinal dysfunction in patients with uremia,im-proves the efficiency of clinical treatment,and has a favorable safety profile.
维普
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