The correlation between metabolic syndrome and its components with the degree of coronary artery stenosis and clinical outcomes in patients with acute myocardial infarction
The correlation between metabolic syndrome and its components with the degree of coronary artery stenosis and clinical outcomes in patients with acute myocardial infarction
Objective To explore the correlation between metabolic syndrome(MS)with the degree of coronary artery stenosis and prognosis in patients with acute myocardial infarction(AMI).Methods There were 726 AMI patients as the subjects,from the Cardiology Department of Xinjiang Uygur Autonomous Region People's Hospital from January 2019 to December 2020.The Gensini score was used to quantitatively assess the degree of coronary artery stenosis and the clin-ical outcome was defined as major adverse cardiovascular events(MACEs).Multiple linear regression was used to ana-lyze the correlation between MS and its components between Gensini score.Multivariate Cox regression was used to ana-lyze the independent risk factors for MACEs.Results There were 348 patients(47.9％)in the MS group and 378 pa-tients(52.1％)in the non-MS group.Compared with the non-MS group,patients in the MS group were older and had more combined hypertension,diabetes,abdominal obesity,dyslipidemia.Waist circumference,systolic blood pressure,fasting blood glucose,blood urea nitrogen,low density lipoprotein cholesterol and Gensini score were higher,hemoglobin levels were lower,clopidogrel utilization rate was higher and the incidence of MACEs was higher,the differences were statistically significant(P＜0.05).Internal comparison showed that Gensini scores were significantly increased in the group of abdominal obesity and elevated fasting blood glucose(P＜0.05).Multiple linear regression analysis results showed that elevated fasting blood glucose and abdominal obesity were independently correlated with Gensini score.Multi-variate Cox regression analysis results showed that:diabetes and abdominal obesity were the independent risk factors for MACEs.Conclusion Patients with AMI complicated by MS were very common.Abnormal glucose metabolism and ab-dominal obesity were closely related to the degree of coronary artery stenosis,and significantly affect the prognosis of pa-tients.
维普
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