Objective To explore the effect of repetitive transcranial magnetic stimulation(rTMS)on cognitive and so-cial function in patients with first-episode schizophrenia,and to provide evidence for clinical treatment.Methods A to-tal of 96 patients with schizophrenia admitted to Hangzhou Seventh People's Hospital from February 2019 to February 2022 they were used the random number table method to randomly divide 48 cases into the observation group(with rTMS true stimulation)and the control group(with pseudo-stimulation),and the scores of cognitive functions[repeatable bat-tery for the assessment of neuropsychological status(RBANS)]and social function[scale of social function in psychosis inpatients(SSPI)]and adverse reactions before and after treatment were compared between the two groups.Results After one month of treatment,immediate memory,delayed memory,speech function,visuospatial structure,attention and total scores of RBANS in observation group were(45.69±2.31),(46.79±3.15),(33.87±2.25),(35.81±2.91),(53.75±3.82),and(237.75±9.7)points,respectively,and in the control group were(38.62±1.29),(42.65± 3.78),(27.75±2.91),(28.62±2.79),(48.85±3.95),(203.96±9.89)points,respectively.The SSPI scale scores of daily living skills,social and sexual activity skills,mobility and interaction,and total SSPI scores in the obser-vation group were(7.84±0.63),(11.76±1.73),(12.72±1.52),and(32.95±1.87)points,respectively,and in the control group were(6.58±0.31),(9.82±1.79),(10.58±1.42),(28.89±1.98)points,respectively.The scores of RBANS and SSPI in the observation group were significantly higher than those in the control group(P＜0.05).There was no significant difference in adverse reactions between the observation group(31.25％,15/48)and the control group(27.08％,13/48),X2=0.202,P=0.653.Conclusion rTMS can effectively improve cognitive and social func-tion in patients with first-episode schizophrenia,and has high safety.
SchizophreniaRepeated transcranial magnetic stimulationCognitive functionSocial function
维普
万方数据
