Objective To analyze the impacts of group mindfulness cognitive therapy on clinical symptoms,sleep quali-ty,and mindfulness awareness in patients of depression with sleep disorders.Methods A total of 193 patients of depres-sion with sleep disorders admitted to the Shaoxing Seventh People's Hospital from January 2023 to September 2023 were se-lected.They were divided into a control group(n=96)and an observation group(n=97)using the random number table method.The control group received routine psychological intervention,while the observation group received group mindful-ness cognitive therapy based on the control group.The depressive symptoms[self rating depression scale(SDS)and Ham-ilton depression scale(HAMD)],sleep quality[Athens insomnia scale(AIS)and insomnia severity index(ISI)],and mindfulness level[five factor mindfulness questionaire(FFMQ)]were compared between the two groups of patients before and after intervention.Results After intervention,the observation group patients exhibited significantly lower scores in SDS(51.20±3.64),HAMD(17.46±2.52),AIS(11.05±2.33)and ISI(12.24±2.80),compared to the control group with scores of 55.64±4.71,19.72±3.43,14.11±3.14 and 15.91±3.17,respectively(P<0.05).Furthermore,the FFMQ scores in all dimensions,total scores of the observation group were significantly higher than those of the control group(P<0.05).Conclusion Group mindfulness cognitive therapy can significantly alleviate depressive symptoms in patients of depression with sleep disorders,and improve sleep quality and mindfulness level.