Effect of scalp acupuncture combined with rehabilitation training on serum MCP-1,ET,sICAM-1 content and nerve function rehabilitation in patients with acute cerebral infarction
Objective To explore the effects of scalp acupuncture combined with rehabilitation training on the levels of monocyte chemoattractant protein-1(MCP-1),endothelin(ET),soluble intercellular adhesion molecule-1(sICAM-1)in the serum of patients with acute cerebral infarction,as well as the National Institute of Health stroke scale(NIHSS),Fugl-Meyer assessment(FMA),and modified Barthel index(MBI)score,and provide a scientific basis for clinical application.Methods The subjects were 78 patients with acute cerebral infarction who were treated at the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from June 2021 to August 2023.They were randomly divided into a con-trol group and an observation group using a random number table method,with 39 patients in each group,and all subjects received the same basic treatment.The control group received general rehabilitation training,while the observation group received scalp acupuncture treatment in combination with the control group for 2 weeks.The serum MCP-1 levels of the two groups before and after intervention,changes in ET,sICAM-1 levels,and NIHSS,FMA,and MBI scores were compared.Results Before treatment,there was no statistically significant difference in the levels of serum MCP-1,ET,sICAM-1,and NIHSS,FMA,and MBI scores between the two groups of patients(P＞0.05).After 2 weeks of treatment,the levels of MCP-1,ET,and sICAM-1 in the serum of both groups significantly decreased(P＜0.05),and the observation group was lower than the control group(P＜0.05);The NIHSS score of the observation group[(5.18±1.68)points]was lower than that of the control group[(7.47±2.25)points,P＜0.001],the FMA score[(47.59±14.62)points]was higher than that of the control group[(34.69±13.34)points,P＜0.001],and the MBI score[(72.28±18.88)points]was higher than that of the control group[(62.59±17.53)points,P＜0.001].Conclusion Scalp acupuncture combined with rehabilita-tion training can significantly reduce the content of MCP-1,ET and sICAM-1 in serum of patients with acute cerebral in-farction,effectively improve the symptoms of neurological impairment,improve the motor function and daily living ability of patients,and promote the rehabilitation of neurological function.
维普
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