Objective To explore the clinical efficacy of combining sodium aescinate tablets with prednisone in the treat-ment of facial neuritis and to explore the clinical value of this scheme in treating facial neuritis.Methods This study en-rolled 60 patients with facial neuropathy from January 2020 to December 2022 at the Department of Neurology,the First Affiliated Hospital of Bengbu Medical University.The patients were randomly divided into two groups using a random number table method:the control group(n=30)received conventional treatment,while the observation group(n=30)received conventional therapy along with the addition of sodium aescinate tablets.After a 30-day treatment period,the clinical effects were assessed by comparing neural function scores,House-Brackman(H-B)rating,and record adverse e-vents between the two groups.Results Following clinical treatment,the observation group showed 9 patients achieving complete recovery(30.0%),10 patients with significant improvement(33.3%),9 were effective(30.0%),and 2 pa-tients with no improvement(6.7%).In the control group,7 patients achieved complete recovery(23.3%),9 patients showed significant improvement(30.0%),6 patients had moderate improvement(20.0%),and 8 patients showed no improvement(26.7%).The difference in total effective rate between the two groups was statistically significant(P<0.05).The mean score of the patients in the observation group was 69.33±14.41,which was higher than that in the control group(61.63±9.45)after treatment,with a statistical difference(P<0.05).There was no significant difference in H-B grade between the observation group and the control group(P>0.05).Additionally,no significant difference in adverse events was observed between the observation group and the control group(P>0.05).Conclusion The combi-nation of sodium aescinate tablets and propionate promotes improved facial neuropathic function and enhances safety.