Consistency analysis of micro-flow imaging and contrast-enhanced ultrasound in evaluating the condition and synovial blood flow of patients with rheumatoid arthritis
Consistency analysis of micro-flow imaging and contrast-enhanced ultrasound in evaluating the condition and synovial blood flow of patients with rheumatoid arthritis
Objective To detect synovial blood flow by micro-flow imaging and contrast-enhanced ultrasound,and ana-lyze the consistency of the two imaging methods in evaluating the condition of patients with rheumatoid arthriti.Methods A total of 50 patients with active rheumatoid arthritis who were treated in Huzhou Third Municipal Hospital from July 2019 to October 2022 were selected as the research objects.All patients were examined by micro-flow imaging and contrast-enhanced ultrasound,and the synovial blood flow of patients was recorded.After 6 months of treatment,the synovial blood flow of patients was evaluated by micro-flow imaging and contrast-enhanced ultrasound again,and.the cor-relation between the results and laboratory indexes was analyzed by Spearman.Results Before treatment,the detection rate of blood flow signals in active patients(Kappa=0.730,P＜0.05)and synovial blood flow evaluation(Kappa=0.797,P＜0.05)were strongly consistent with each other in the micro-flow imaging and contrast-enhanced ultrasound.After 6 months'treatment,the detection rate of blood flow signals(Kappa=0.845,P＜0.05)and synovial blood flow e-valuation(Kappa=0.741,P＜0.05)of patients in remission were both consistent in the micro-flow imaging and contrast-enhanced ultrasound.Micro-flow imaging and contrast-enhanced ultrasound were positively correlated with erythrocyte sedimentation rate,CRP and rheumatoid factor levels in both active and remission stages(P＜0.05),and the correlation of micro-flow imaging was stronger than that of contrast-enhanced ultrasound.Conclusion Micro-flow imaging and con-trast-enhanced ultrasound have strong consistency in the assessment of synovial blood flow in patients with rheumatoid ar-thritis in active stage and remission stage,and both have clinical guiding significance for disease assessment.
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