Objective Ultrasound features can be used to predict early missed abortion,but there is no research to ex-plain the value of transvaginal ultrasound features in predicting early missed abortion in different gestational weeks,so this study established a prediction model of early missed abortion based on ultrasound features and analyzed its prediction effi-ciency.Methods A total of 251 pregnant women diagnosed as intrauterine singleton pregnancy by transvaginal ultra-sound from January 2021 to February 2022 in Huzhou Maternal and Child Health Hospital were included as the research objects.The gestational sac(GS),yolk sac(YS)diameter,crown-rump length(CRL)and fetal heart rate(HR)were detected by the ultrasound until the 10th week of pregnancy.Two hundred and fifty-one patients were followed up and re-corded the incidence of missed abortion in 11-12 weeks and the levels of GS,YS,CRL and HR.Logistic regression data package in SPSS 22.0 software was used to screen the influencing factors of early missed abortion,and a logistic regres-sion prediction model was constructed to draw ROC curve to analyze the prediction efficiency.Results Pregnant women were divided into abortion group(43 cases)and continued pregnancy group(208 cases)according to whether the pa-tients had early missed abortion.The results of multivariate logistic regression showed that testosterone(OR=0.452),estradiol(OR=1.422)and progesterone(OR=1.442)were all predictors of early missed abortion(P＜0.05).The pre-diction model based on clinical features predicted the area under the curve of early missed abortion was 0.815,the pre-diction model of 6-week ultrasound characteristics was 0.801,the prediction model of 7-week ultrasound characteristics was 0.926,the prediction model of 8-week ultrasound characteristics was 0.906,the prediction model of 9-week ultra-sound characteristics was 0.883 and the prediction model of 10-week ultrasound characteristics was 0.924.According to Delong analysis,the area under the curve of the ultrasonic feature prediction model at the 7th and 10th weeks of pregnan-cy is higher than that of the prediction model based on clinical features(P＜0.05).Conclusion The prediction model based on ultrasound characteristics of 6-10 weeks can be used to predict missed abortion in 11-12 weeks of pregnancy,but the prediction value of the prediction model based on ultrasound characteristics of 7-week and 10-week of pregnancy are higher than that based on clinical characteristics,and the prediction value of other pregnancy ultrasound characteris-tics prediction models is equivalent to that based on clinical characteristics,among which YS is the strongest ultrasound characteristic index to predict early missed abortion.
关键词
早期稽留流产/超声特征/妊娠/预测模型
Key words
Early missed abortion/Ultrasonic characteristics/Pregnancy/Prediction model
维普
万方数据