首页|不同电磁刺激方案干预脑卒中后假性球麻痹吞咽障碍的对比研究

不同电磁刺激方案干预脑卒中后假性球麻痹吞咽障碍的对比研究

A comparative study of different electromagnetic stimulation schemes in the intervention of post stroke pseudobulbar paralysis swallowing disorders

扫码查看
目的 对比不同组合的电磁刺激方案治疗假性球麻痹的疗效,为治疗方案的优化提供借鉴.方法 选择2022年1月-2023年3月绵阳市中心医院脑卒中后假性球麻痹患者120例,采用随机数字表法分为对照组、经颅直流电刺激(tDCS)+表面神经肌肉电刺激(NMES)组、重复经颅磁刺激(rTMS)+NMES组、tDCS+rTMS组,每组30例.对照组给予常规治疗,其余3组进行不同组合的电磁刺激.评估藤岛一郎吞咽疗效评分、标准吞咽功能量表(SSA)、吞咽困难生活质量量表(SWAL-QOL);纤维光学内镜检查(FEES)下的PAS分级;舌骨喉复合体动度;平均肌电值(AEMG).结果 治疗后rTMS+NMES组藤岛一郎评分[(5.04±0.79)分]高于对照组[(3.51± 0.64)分]、tDCS+NMES 组[(4.19±0.79)分]、tDCS+rTMS 组[(3.96±0.73)分];rTMS+NMES 组 SSA 均低于其余3组(P<0.05).而SWAL-QOL评分,rTMS+NMES组仅高于对照组,与其余2组差异无统计学意义;PAS分级rTMS+NMES组均优于其余3组(P<0.05);在骨喉复合体动度,rTMS+NMES组舌骨上移和前移距离均高于其余3组(P<0.05);在 sEMG 检查中,rTMS+NMES 组高于对照组和 tDCS+NMES 组(P<0.05).结论 rTMS+NMES 组合治疗假性球麻痹的整体效果更优.
Objective To compare the efficacy of different combinations of electromagnetic stimulation schemes in the treatment of pseudobulbar palsy,and provide reference for the optimization of treatment plans.Methods A total of 120 patients with pseudobulbar palsy after stroke were selected at Mianyang Central Hospital from January 2022 to March 2023.They were randomly divided into four groups:a control group,a group receiving transcranial direct current stimula-tion(tDCS)+neuromuscular electrical stimulation(NMES),a group receiving repetitive transcranial magnetic stimula-tion(rTMS)+NMES,and a group receiving tDCS+rTMS.Each group consisted of 30 cases.The control group received routine treatment,while the other three groups received different combinations of electromagnetic stimulation.The evalua-tion included the swallowing efficacy score of Ichiro Fujishima,the standardized swallowing assessment(SSA),the swal-lowing-quality of life(SWAL-QOL),PAS grading under fiberoptic endoscopic evaluation of swallowing(FEES),hyoid laryngeal complex motility,and average surface electromyography(AEMG).Results After treatment,the rTMS+NMES group exhibited significantly higher Ichiro Fujishima's swallowing efficacy scores(5.04±0.79)compared to the control group(3.51±0.64),tDCS+NMES group(4.19±0.79),and tDCS+rTMS group(3.96±0.73).The rTMS+NMES group also demonstrated a significantly lower SSA than the other three groups(P<0.05).In terms of SWAL-QOL,the rTMS+NMES group only showed improvement compared to the control group,with no difference when compared to the other two groups.However,in PAS assessment,the rTMS+NMES group was superior to the other three groups(P<0.05).Regarding mobility of the bone throat complex,the rTMS+NMES group displayed a greater distance of upward and forward movement of the hyoid bone compared to all other groups(P<0.05).Additionally,rTMS+NMES group re-vealed higher sEMG than both control and tDCS+NMES groups(P<0.05).Conclusion The combination of rTMS+NMES has the best overall effect in the treatment of pseudobulbar palsy.

Electromagnetic stimulationStrokePseudobulbar paralysisSwallowing disorders"Central Peripheral"

罗雅丽、陈劲松、陈莎莎、苏牟潇、白洁、刘双

展开 >

绵阳市中心医院康复医学科,四川绵阳 621000

电磁刺激 脑卒中 假性球麻痹 吞咽障碍 "中枢-外周"

康复医学四川省重点实验室开放基金

KFYX-SZDSYS-06

2024

中华全科医学
中华预防医学会,安徽省全科医学会

中华全科医学

CSTPCD
影响因子:1.688
ISSN:1674-4152
年,卷(期):2024.22(4)
  • 18